Gabriela Radulescu

Gabriela provides medical leadership for sponsor clinical trials, operational oversight for research and development projects, and medical input to the business development teams.

Background

Gabriela obtained her medical degree at the University of Medicine and Pharmacy Iuliu Hatieganu in Cluj – Napoca, Romania. Since then, she has acquired more than 20 years of experience working in the pharmaceutical industry in Canada in various leadership roles and across multiple functions including medical affairs, drug safety and pharmacovigilance, clinical research and real world evidence, and patient support programs. Prior to joining Alimentiv, Gabriela led a team of scientific professionals as a Medical Affairs Director in IBD.

Achievements

Since joining Alimentiv, through her multidisciplinary experience, Gabriela has been able to bring significant contributions to the development and implementation of organizational strategies and best practices. Her focus on the medical research and development area ensures a continued adherence to delivering high-quality research and science, superior customer service and people development.

Ethos

“I approach my role with the conviction that what we do matters for patients and physicians, and through our work we advance our mission to support human health. I believe it is important that every member of the Alimentiv team is authentic and brings their full contribution to the success of the organization.”

Guangyong (GY) Zou

After completing PhDs in Biostatistics and Plant Science from the University of Connecticut, Dr. Zou joined Alimentiv in September 2002. He is currently Professor of Epidemiology and Biostatistics at Western University.

Background

Dr. Zou oversees statistical support for Medical R&D programs, as well as Alimentiv IBD clinical research.

He has over 20 years of experience designing and analyzing clinical trials, including cluster randomization trials. His research has primarily focused on development and evaluation of statistical methods for medical research. At Alimentiv, he’s also researching endpoint development and validation, larger-scale effectiveness research and strategy trials.

He has published over 150 peer-reviewed articles, many of which have impacted medical and epidemiologic research. A single-authored 2004 article on regression models for estimating risk ratios has already received close to 3,000 citations.

Achievements

Dr. Zou wrote a 2004 paper on estimation of risk ratios that’s been cited close to 5,000 times, and a 2012 paper that Alimentiv uses to design reliability studies.

Ethos

“Results are only as good as the statistical methodology used to obtain them. My goal is to continuously create good statistical methodology for medical research.”

Niels Vande Casteele

Dr. Vande Casteele established the precision medicine group where he oversees the development, validation and operationalization of clinical pharmacology & translational medicine research tools to ascertain efficient drug development.

Background

Dr. Vande Casteele holds a Bachelor of Pharmaceutical Sciences and Masters in Drug Design and Development from the University of Leuven, Belgium. He performed research in the fields of molecular biology at the Institute of Medical Sciences, University of Aberdeen, Scotland, and in immunology at Sanquin, University of Amsterdam, the Netherlands. He obtained his Ph.D. in Pharmaceutical Sciences based on his research dissertation entitled “Optimizing anti-TNF therapy in inflammatory bowel disease patients, a step towards personalized dosing” at the University of Leuven, Belgium.

Dr. Vande Casteele currently holds an appointment as Assistant Professor of Medicine at the University of California San Diego, where he teaches a course on Biologics and Biosimilars Drug Development. His main research efforts focus on clinical pharmacology and translational medicine of small and large molecules used in the treatment of chronic inflammatory diseases, with an emphasis on characterizing pharmacokinetics and pharmacodynamics in relation to treatment outcomes in clinical practice and drug development.

Achievements

Dr. Vande Casteele has published over 100 peer reviewed research articles and book chapters; has given over 30 invited lectures; and has received awards for his research contributions from distinguished professional organizations such as the European Crohn’s and Colitis Organization (ECCO), the American Gastroenterological Association (AGA), the Crohn’s and Colitis Foundation (CCF) and United European Gastroenterology (UEG) association.

Ethos

“Just like you have to climb the mountain in order to see the view, doing scientific research requires inquisitiveness, adaptiveness and a team approach to overcome hurdles in order to reach the objective.”