Alimentiv Has The Right Solution For Your Project

At Alimentiv, we foster innovation in the world of GI-related Clinical Trials by investing our profits back into R&D and producing novel medical imaging solutions to unmet needs.

Our imaging product line is growing.

New product development, including automated HD video capture, is the focus of our CIMS product line expansion. Our deep scientific and operational expertise, combined with built-for-purpose technology solutions like Notō, an end-to-end imaging workflow platform is the foundation for our expanding portfolio of technology solutions for drug development programs.

Alimentiv is the right partner to help you successfully run projects from an early stage through post approval.

Our products are a combination of technological developments coupled with deep medical expertise with a goal to improve clinical trial timelines and improve the efficiency with which disease activity can be measured. Alimentiv’s new products are helping to transform clinical trial practices.

Why Choose Alimentiv?

Deep Medical And Scientific Knowledge

Proven Operational Excellence

Exceptional Customer Service

Industry Leading Technology for all modalities

Alimentiv is the industry-leading provider of imaging solutions for clinical trials in IBD and EGID, with solutions for endoscopy, histopathology, and MR imaging.

Our Technology Solutions For GI Clinical Trials:

At Alimentiv, we understand the importance of accurate and reliable medical imaging in developing new treatments for Gastrointestinal (GI) health conditions.

That’s why we offer a comprehensive portfolio of imaging solutions designed to support the unique needs of your clinical trial.

Our solutions include professional services and cutting-edge technology, ensuring the standardized acquisition of imaging data, quality control, and expert Central Reader evaluation.

Our full suite of imaging modalities includes endoscopy, digital pathology, magnetic resonance, and intestinal ultrasound, each of which can be customized to meet the specific requirements of your trial.

Our team of experts can guide you through the entire imaging process, from trial design and protocol development to study execution and closeout.

Let us help you achieve success in your clinical trial with our innovative and reliable imaging solutions. Contact our business development team today to learn more about how Alimentiv can support your study.

Imaging Product Line

CIMS - Endoscopy Imaging Solutions

At Alimentiv, we specialize in providing advanced medical imaging solutions that meet the unique needs of Gastroenterology (GI) clinical trials. Our CIMS Endoscopy technology is a leading solution for central image management in global clinical trials, providing standardized video acquisition, quality control, and expert assessment of endoscopic disease activity by gastroenterologists.

As the pioneer in developing, validating, and implementing endoscopic central imaging solutions in IBD clinical trials, we have been providing this solution since 2007, and it has become the global leader in central endoscopy reading services. Our research has shown that central reading reduces the placebo response and increases data quality.

In 2023 a significant enhancement to the CIMS technology was completed to add high-definition (HD) video capture capability in response to new draft guidance from the FDA on developing drugs for the treatment of Ulcerative Colitis and Crohn's disease. We are the first service provider to bring an HD video capture solution designed specifically for clinical trials to the market.

Our CIMS Endoscopy technology offers a range of features and benefits that make it the perfect solution for your clinical trial, including:

  • Customization to meet your clinical trial protocol requirements
  • Compliance with FDA 21 CFR part 11 and other regulatory standards
  • Secure and encrypted video recordings
  • Compatible with endoscopy video processing units in use in over 60 countries around the world
  • Easy to set up with a simple user interface and real-time verification of video capture

CIMSPLUS technology is designed to make the process of endoscopic imaging in clinical trials more efficient, reliable, and accurate to help you achieve success in your clinical trial. With our expert team of professionals, you can rest assured that your endoscopic imaging needs are in good hands.

CIMSPLUS is the enhanced version of Alimentiv's industry-leading CIMS Endoscopy video capture and viewing technology. The launch of this viewing technology was designed to meet the unique needs of Gastroenterology (GI) clinical trials. CIMSPLUS offers standardized video acquisition, quality control, and expert assessment of endoscopic disease activity by gastroenterologists, with added benefits over the original CIMS solution.

Indications:

  • Crohn's Disease
  • Ulcerative Colitis
  • Pouchitis
  • Eosinophilic Gastrointestinal Disease (EGID)

Scoring Indices:

  • SES-CD
  • CDEIS
  • UCEIS
  • Mayo Endoscopic Subscore (MES)
  • Modified Mayo Score
    EREFS

Don't let inadequate imaging hold you back from developing new treatments for Gastroenterology (GI) health conditions. Choose Alimentiv's CIMS Endoscopy technology for a reliable and innovative solution that will support the success of your clinical trial. Contact our business development team to learn more about how we can help.

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Lucidity - Histopathology Imaging Solution

At Alimentiv Clinical Trials, we understand that sometimes the most important information about a disease is hidden from plain view. That's why we offer a Central Reading service for whole slide images of histopathology samples. Our service is specifically designed for the assessment of disease activity in conditions such as Inflammatory Bowel Disease (IBD), Eosinophilic Esophagitis (EoE), and Nonalcoholic Steatohepatitis (NASH) and may prove to be beneficial for other indications as research continues.

Our histopathology solution is an integrated biopsy sample management workflow and image management software that was built in partnership with international expert GI pathologists and leading imaging software developers. We provide a distinctive and competitive service for centralized histological assessment of disease activity, starting at tissue processing (through our preferred lab, AcelaBio) and digitization of slides. We utilize our proprietary image management software, Lucidity, which is 21 CFR11 compliant, ensuring slide images are fully auditable, protected, and reliable.

Once uploaded to Lucidity, images are securely encrypted, quality controlled and made available to our expert Central Readers who perform centralized assessment and enter their scoring data into a validated EDC system, allowing for expedited data sharing to meet our client's needs. Trust in our Central Reading service for histopathology to provide the detailed and accurate information you need to make informed decisions about your clinical trial.

Indications:

  • Crohn's Disease
  • Ulcerative Colitis
  • Pouchitis
  • Eosinophilic Esophagitis (EoE)
  • Nonalcoholic Steatohepatitis (NASH)

Scoring Indices:

  • Geboes Score
  • Robarts Histopathology Index (RHI)
  • Nancy Histological Index (NHI)
  • Pouchitis Disease Activity Index (PDAI)
  • Global Histological Disease Activity Score (GHAS)
  • Eosinophilic Esophagitis Histological Scoring System (EoEHSS)
  • Peak Eosinophil Count (PEC)
  • NAFLD Activity Score (NAS)
  • NASH Clinical Research Network (CRN) Fibrosis Score
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Notō - Multi-Modal Imaging Solution

Notō is Alimentiv's proprietary, customized end-to-end solution supporting image review, central reader scoring workflow, and data capture across all our imaging modalities. With Notō you can enjoy the benefits of transparent, real-time access to scoring data and images, dynamic reporting capabilities, and streamlined, automated workflows allowing multi-platform integration with Single Sign On (SSO).

Notō accelerates the study start-up process by reducing database development timelines. This allows faster and more efficient data management, allowing you to focus on other aspects of your clinical trial - Trust Notō to manage your data with precision and accuracy.

Request a link to our guided Notō demo

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Non-Invasive Imaging

At Alimentiv Clinical Trials, we constantly strive to provide safer and more non-invasive methods for disease activity assessment. We offer our clients Magnetic Resonance Imaging (MRI) / Enterography (MRE) as a non-invasive imaging option. MRE has high diagnostic accuracy, does not require exposure to ionizing radiation, and is considerably less invasive than endoscopy, making it an ideal option for serial assessments in clinical trials.

Indications:

  • Perianal Fistulizing Crohn's Disease
  • Small Bowel Crohn's Disease
  • Fibrostenotic Crohn's Disease

Scoring Indices:

  • Van Assche
  • Magnetic Resonance Index of Activity (MaRIA) Scoring System
  • Magnifi-CD
  • Constrict Score
  • Stricturing Radiology Index (SRI)

In addition to MRE, we are also excited to announce our partnership with the International Bowel Ultrasound (IBUS) Group e.V. to offer Intestinal Ultrasound (IUS) central reading services in clinical trials of adults and children with Inflammatory Bowel Disease (IBD).

IUS is a cost-effective, tolerable, and repeatable non-invasive monitoring tool that has shown great accuracy in assessing IBD disease activity and complications. It may also detect early treatment responses that routine colonoscopy cannot identify.

This partnership aims to deliver synergistic value to IBD research by combining our clinical trial design expertise and intestinal ultrasound. Our partnership with IBUS will help to advance knowledge and experience in the field of IUS for patients with IBD, and the implementation of IBUS ultrasound central reading services in Alimentiv sponsor-funded IBD clinical trials is expected to be available in 2023.

Trust in our non-invasive imaging options to provide accurate and safe assessments of disease activity in your clinical trial.

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Learn More About Our Professional Services

We pride ourselves on our ability to provide customized imaging solutions that meet each client's unique needs. Our team of interdisciplinary experts collaborates to tailor each solution, ensuring efficient image processing and centralized assessment of videos and/or images. By working together, we are able to deliver results that are not only accurate but also reliable and delivered in a timely manner. Trust in our team to provide the support you need for your imaging needs.

Alimentiv utilizes its far-reaching network to accelerate the path to improved clinical trial outcomes and efficiency. Dedicated to transforming human health, ongoing development and the launch of our industry-leading imaging solutions are part of our investment towards improvements in medical and scientific knowledge.

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