Publications Responsiveness of Endoscopic Indices of Disease Activity for Crohn’s Disease Citation Khanna R, Zou G, Stitt L, Feagan BG, Sandborn WJ, Rutgeerts P, McDonald JWD, Dubcenco E, Fogel R, Panaccione R, Jairath V, Nelson S, Shackelton LM, Huang B, Zhou Q, Robinson AM, Levesque BG, D'Haens G. Responsiveness of Endoscopic Indices of Disease Activity for Crohn's Disease. Am J Gastroenterol. 2017 Oct;112(10):1584-1592. doi: 10.1038/ajg.2016.580. Epub 2017 Jan 10. Erratum in: Am J Gastroenterol. 2017 Jun;112(6):975. PMID: 28071654. Abstract Objectives: The Crohn’s Disease Endoscopic Index of Severity (CDEIS) and the Simple Endoscopic Score for Crohn’s Disease (SES-CD) are commonly used to assess Crohn’s disease (CD) activity; however neither instrument is fully validated. We evaluated the responsiveness to change of the SES-CD and CDEIS using data from a trial of adalimumab, a drug therapy of known efficacy. Tags Adalimumab, Anti-Inflammatory Agents, Crohn's Disease, Diagnosis, Drug Therapy, Endoscopy, Gastrointestinal, Prognosis, Research Design Read More
