Publications Placebo Rates in Randomized Controlled Trials of Pouchitis Therapy Citation Athayde J, Davies SC, Parker CE, Guizzetti L, Ma C, Khanna R, Feagan BG, Jairath V. Placebo Rates in Randomized Controlled Trials of Pouchitis Therapy. Dig Dis Sci. 2018 Oct;63(10):2519-2528. doi: 10.1007/s10620-018-5199-9. Epub 2018 Jul 11. PMID: 29995184. Abstract Background: Approximately half of the patients with ulcerative colitis (UC) who undergo restorative proctocolectomy develop pouchitis within 10 years of surgery. Currently, there are no approved pouchitis treatments. It is important to quantify, and ultimately minimize, placebo rates to design and conduct efficient pouchitis trials. Tags Placebo Effect, Pouchitis, Therapy, Trial Design, Ulcerative Colitis Read More