Abstract

Background: Approximately half of the patients with ulcerative colitis (UC) who undergo restorative proctocolectomy develop pouchitis within 10 years of surgery. Currently, there are no approved pouchitis treatments. It is important to quantify, and ultimately minimize, placebo rates to design and conduct efficient pouchitis trials.

Tags

Placebo Effect, Pouchitis, Therapy, Trial Design, Ulcerative Colitis

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