Abstract

Background: Incorrect classification of outcomes in clinical trials can lead to biased estimates of treatment effect and reduced power. Ensuring appropriate adjudication methods to minimize outcome misclassification is therefore essential. While there are many reported adjudication approaches, there is little consensus over which approach is best.

Tags

Advisory Committees, Bias, Central assessor, Colonoscopy, Computer Simulation, Diagnosis, Endpoint adjudication committee, Endpoint Determination, Endpoint review committee, Misclassification, Outcome adjudication, Outcome Assessment, Randomized controlled trial, Therapy, Treatment Outcome, Ulcerative Colitis

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