Background: It is important to minimize placebo rates in randomised controlled trials (RCTs) to efficiently detect treatment differences between interventions. Historically, high placebo rates have been observed in clinical trials of ulcerative colitis (UC). A better understanding of factors influencing placebo rates may lead to more informed clinical trial design.


Diagnosis, Complications, Placebo Effect, Gastrointestinal Hemorrhage, Anti-Inflammatory Agents, Maintenance Chemotherapy, Anti-Inflammatory Agents Non-Steroidal, Drug Therapy, Aminosalicylic Acids, Ulcerative Colitis, Induction Chemotherapy, therapeutic use, Biological Products

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