Background: It is important to minimize placebo rates in randomised controlled trials (RCTs) to efficiently detect treatment differences between interventions. Historically, high placebo rates have been observed in clinical trials of ulcerative colitis (UC). A better understanding of factors influencing placebo rates may lead to more informed clinical trial design.


Aminosalicylic Acids, Anti-Inflammatory Agents, Anti-Inflammatory Agents Non-Steroidal, Biological Products, Complications, Diagnosis, Drug Therapy, Gastrointestinal Hemorrhage, Induction Chemotherapy, Maintenance Chemotherapy, Placebo Effect, therapeutic use, Ulcerative Colitis

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