Publications
Placebo rates in randomized controlled trials of proctitis therapy: A systematic review and meta-analysis
Citation
De Silva TA, Alphonsus L, Ma C, Hogan M, Sedano R, Narula N, Danese S, Peyrin-Biroulet L, MacDonald JK, Singh S, Jairath V. Placebo rates in randomized controlled trials of proctitis therapy: A systematic review and meta-analysis. J Crohns Colitis. 2022 Aug 5:jjac109. doi: 10.1093/ecco-jcc/jjac109. Epub ahead of print. PMID: 35930405.
Abstract
Background and aims: Treatment options for proctitis are limited. To assist trial design for novel therapeutics, we conducted a systematic review and meta-analysis of proctitis randomized controlled trials (RCTs) to quantify placebo rates and identify factors influencing them.
