Background & aims: Endpoints in randomized controlled trials (RCTs) of Crohn’s disease (CD) are changing. We performed a systematic review of efficacy and safety outcomes reported in placebo-controlled RCTs of patients with CD.


Treatment Outcome, Adverse Effects, Therapy, Diagnosis, Anti-Inflammatory Agents, RCT, Effects, Inflammatory Bowel Disease, Treatment, IBD, Crohn's Disease, therapeutic use

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