Abstract

Background & aims: Agents are being developed for treatment of eosinophilic esophagitis (EoE). However, it is not clear what outcome measures would best determine the efficacy and safety of these agents in clinical trials. We performed a systematic review of outcomes used in randomized placebo-controlled trials of EoE and we estimate the placebo response and rates of remission.

Tags

Anti-Inflammatory Agents, drug, Drug Therapy, Endoscopy, Eosinophilic Esophagitis, Esophagus, Histology, inflammation, Outcome Assessment, Pathology, Patient-reported Outcomes, Placebo, Treatment Outcome

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