Background: Combining clinical, endoscopic, and histological data associated with ulcerative colitis disease activity in a composite index could be a more sensitive way to detect efficacy in small numbers of patients during early drug development. Our aim was to derive and externally validate a novel index for this purpose.


Complications, Etiology, Gastrointestinal Hemorrhage, Drug Development, Drug Therapy, Ulcerative Colitis, Pathology, Endoscopy, Diagnosis

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