Abstract

Background:¬†Fibrotic stricture is a common complication of Crohn’s disease (CD) affecting approximately half of all patients. No specific anti-fibrotic therapies are available; however, several therapies are currently under evaluation. Drug development for the indication of stricturing CD is hampered by a lack of standardised definitions, diagnostic modalities, clinical trial eligibility criteria, endpoints and treatment targets in stricturing CD.

Tags

Diagnosis, Colon, Intestines, Complications, Intestinal Obstruction, Etiology, Crohn's Disease, Surgery, Pathology, Catheterization, Fibrosis, Dilatation, Endoscopy, Therapy

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