Abstract

Background: Incorrect classification of outcomes in clinical trials can lead to biased estimates of treatment effect and reduced power. Ensuring appropriate adjudication methods to minimize outcome misclassification is therefore essential. While there are many reported adjudication approaches, there is little consensus over which approach is best.

Tags

Endpoint adjudication committee, Endpoint review committee, Misclassification, Outcome adjudication, Ulcerative Colitis, Randomized controlled trial, Colonoscopy, Advisory Committees, Treatment Outcome, Bias, Therapy, Endpoint Determination, Diagnosis, Computer Simulation, Outcome Assessment, Central assessor

Read More